Publication Year: 2007 - 2008


Eckol protects V79-4 lung fibroblast cells against γ-ray radiation-induced apoptosis via the scavenging of reactive oxygen species and inhibiting of the c-Jun NH2-terminal kinase pathway.
Zhang R, Kang KA, Piao MJ, Ko DO, Wang ZH, Lee IK, Kim BJ, Jeong IY, Shin T, Park JW, Lee NH, Hyun JW.
Eur J Pharm. 2008, 591(1-3), 114-123.

Modulation of apoptosis of eckol against ionizing radiation in mice.
Park E, Lee NH, Joo HG, Jee Y.
Biochem Biophys Res Commun. 2008, 372(4), 792-797.

Radioprotective properties of eckol against ionizing radiation in mice.
Park E, Ahn GN, Lee NH, Kim JM, Yun JS, Hyun JW, Jeon YJ, Wie MB, Lee YJ, Park JW, Jee Y.
FEBS Lett. 2008, 582(6), 925-930.

Protective effect of phlorotannin components phlorogluciol and eckol on radiation- induced intestinal injury in mice.
Moon CM, Kim SH, Kim JC, Hyun JW, Lee NH, Park JW, Shin T.
Phytother Res. 2008, 22(2), 238-242.

Inhibitory efects of triphlorethol-A on MMP-1 induced by oxidative stress in human keratinocytes via ERK and AP-1 inhibition.
Kang KA, Zhang R, Piao MJ, Ko DO, Wang ZH, Lee IK, Kim BJ, Shin T, Park JW, Lee NH, Yoo BS, Hyun JW.
J Toxicol Environ Health. 2008, 7(15), 992-999.

Anti-hyperlipidemic dffect of an edible brown algae, Ecklonia stolonifera, and its constituents on poloxamer 407-induced hyperlipidemic and cholesterol-fed rats.
Yoon NY, Kim HR, Chung HY, Choi JS.
Arch Pharm Res. 2008, 31(12), 1564-1571.

Antidiabetic antioxidant effects of polyphenols in brown alga Ecklonia stolonifera in genetecally diabetic
KK-Ay mice.
Iwai K.
Plant Foods Hum Nutr. 2008, 63(4), 163-169.

Immunomodulatory effects of an enzymatic extract from Ecklonia cava on murine splenocytes.
Ahn G, Hwang I, Park E, Kim J, Jeon YJ, Lee J, Park JW, Jee Y.
Mar Biotechnol. 2008, 10(3), 278-289.

Effects of Ecklonia cava ethanolic extracts on airway hyperresponsiveness and inflammation in a murine asthma model: Role of suppressor of cytokine signaling.
Kim SK, Lee DY, Jung WK, Kim JH, Choi I, Park SG, Seo SK, Lee SW, Lee CM, Yea SS, Choi YH, Choi IW.
Biomed & Pharmacother. 2008, 62(5), 289-296.

Anti-allergic effects of phlorotannins on histamine release via binding inhibition between IgE and FcεRI.
Li Y, Lee SH, Le AT, Kim MM, Kim SK.
J Agric Food Chem. 2008, 56(24), 12073-12080.

Anti-allergic effects of the brown alga Eisenia arborea on brown Norway rats.
Sugiura, Y, Matsuda K, Okamoto T, Kakinuma M, Amano H.
Fisheries Sci. 2008, 74, 180-186.

Anti-HIV-1 activity of phloroglucinol derivative 6,6'-bieckol from Ecklonia cava.
Artan M, Karadeniz F, Lee SH, Kim MM, Kim SK.
Bioorg Med Chem. 2008, 16(17), 7921-7926.

Identification of chemical structure and free radical scavenging activity of diphlorethohydroxycarmalol isolated from a brown alga, Ishige okamurae.
Heo SJ, Kim JP, Jung WK, Lee NH, Kang HS, Jun EM, Park SH, Kang SM, Lee YJ, Park PJ, Jeon YJ.
J Microbiol Biotechnol. 2008, 18(4), 676-681.

Antioxidant activities of phlorotannins isolated from Japanese Laminariaceae.
Shibata T, Ishimaru K, Kawaguchi S, Yoshikawa H, Hama Y.
J Appl Phycol. 2008, 20, 705-711.

Acetyl- and butyrylcholinesterase inhibitory activities of sterols and phlorotannins from Ecklonia Stolonifera.
Yoon NY, Chung HY, Kim HR, Choi JA,
Fisheries Science. 2008, 74, 200-207.


Triphlorethol-A induces heme oxygenase-1 via activation of ERK and NF-E2 related factor 2 transcription factor.
Kang KA, Lee KH, Park JW, Lee NH, Na HK, Surh YJ, You HJ, Chung MH, Hyun JW.
FEBS Lett . 2007, 581(10), 2000–2008.

Antioxidant activities of phlorotannins purified from Ecklonia cava on free radical scavenging using ESR and H2O2-mediated DNA damage.
Ahn GN, Kim KN, Cha SH, Song CB, Lee J, Heo MS, Yeo IK, Lee NH, Jee YH, Kim JS.
Eur Food Res Technol. 2007, 226(1), 71–79.

Anti-allergic phlorotannins from the edible brown alga, Eisenia arborea.
Sugiura, Y, Matsuda K, Yamada Y, Nishikawa M, Shioya K, Katsuzaki H, Imai K, Amano H,
Food Sci Technol Res. 2007, 13(1), 54-60.

Isolation of a New Phlorotannin, Fucodiphlorethol G, from a Brown Alga Ecklonia cava.
Ham YM, Baik JS, Hyun JW, Lee NH,
Bull Korean Chem Soc. 2007, 28(9), 1595-1597.